Document Detail

Congenital heart disease in relation to pulmonary hypertension in paediatric practice.
MedLine Citation:
PMID:  16153566     Owner:  NLM     Status:  MEDLINE    
Pulmonary hypertension (PHT) is a well recognised feature of untreated congenital heart disease. This article will review the causes, known mechanisms, appropriate investigations and current therapies for PHT. The reader will understand the difference between PHT due to high pulmonary blood flow and PHT that is due to high pulmonary vascular resistance. The former is best treated by surgical or catheter intervention, whereas for the latter (Eisenmenger syndrome) only palliation is possible with medication or transplantation. Echocardiography and electrocardiography (ECG) should be performed in any child where there is a possibility of pulmonary hypertension, especially with long standing chronic lung disease and minor left to right shunt. Often these children may have dual pathology and their investigation and management may be a complex interaction between cardiac and respiratory therapists. New treatments and new techniques of assessment are now available and this may lead to improved recognition of PHT and prevention of long term disability as a result.
Robert M R Tulloh
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Paediatric respiratory reviews     Volume:  6     ISSN:  1526-0542     ISO Abbreviation:  Paediatr Respir Rev     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-12     Completed Date:  2005-11-15     Revised Date:  2009-10-14    
Medline Journal Info:
Nlm Unique ID:  100898941     Medline TA:  Paediatr Respir Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  174-80     Citation Subset:  IM    
Department of Congenital Heart Disease, Paul O'Gorman Building, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ, UK.
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MeSH Terms
Chronic Disease
Heart Defects, Congenital / complications*
Hypertension, Pulmonary / epidemiology,  etiology*,  physiopathology,  therapy
Respiratory Mechanics
Risk Factors
Transposition of Great Vessels / surgery
Vascular Resistance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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