| Congenital heart defects and maternal derangement of homocysteine metabolism. | |
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MedLine Citation:
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PMID: 10586186 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Methionine loading tests and folate, vitamin B(6), and vitamin B(12) analyses were performed in 27 mothers of children with congenital heart defects. Median fasting plasma homocysteine concentrations were significantly higher in the study group as compared with 56 control subjects (P =.0001). Maternal hyperhomocysteinemia may be a risk factor for congenital heart defects. |
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Authors:
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L Kapusta; M L Haagmans; E A Steegers; M H Cuypers; H J Blom; T K Eskes |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of pediatrics Volume: 135 ISSN: 0022-3476 ISO Abbreviation: J. Pediatr. Publication Date: 1999 Dec |
Date Detail:
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Created Date: 1999-12-30 Completed Date: 1999-12-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 773-4 Citation Subset: AIM; IM |
Affiliation:
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Children's Heart Center, Department of Pediatrics, University Hospital Nijmegen, Nijmegen, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Case-Control Studies Female Heart Defects, Congenital / epidemiology* Homocysteine / blood* Humans Infant Mothers Postpartum Period Risk Factors |
| Chemical | |
Reg. No./Substance:
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454-28-4/Homocysteine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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