Document Detail


Congenital heart defects in Kabuki syndrome.
MedLine Citation:
PMID:  23558868     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: Kabuki syndrome (KS) is an entity of multiple congenital malformations with mental retardation with undetermined etiology. Congenital heart defects are one of the clinical manifestations of KS with insuffi cient elucidations.
METHODS: Literature of congenital heart defects associated with KS was comprehensively retrieved, collected and reviewed. The clinical features of the congenital heart defects in the patients with KS were summarized.
RESULTS: Congenital heart defects were one of the clinical manifestations of KS with 90.6% of the patients being diagnosed prenatally or at an early age. Left-sided obstructions/aortic dilation and septal defects were the fi rst two types of anomalies, accounting up to 46.1% and 32.9%, respectively. The most common congenital heart defects were coarctation of the aorta, and atrial and ventricular septal defects. Fifteen (19.7%) patients received surgical repair of congenital heart defects at a mean age of 0.8 ± 1.3 years.
CONCLUSIONS: Congenital heart defects are one of the clinical manifestations of KS with 90.6% of the patients being diagnosed prenatally or at an early age. About 20% of the patients warranted surgical repair of the heart defects. Patients with KS require close follow-up in terms of their etiology, clinical presentations and long-term prognosis.
Authors:
Shi-Min Yuan
Related Documents :
21622828 - Repeated sauna therapy attenuates ventricular remodeling after myocardial infarction in...
22549008 - Absence of actions of commonly used chinese herbal medicines and electroacupuncture on ...
16919518 - Secondary prevention of coronary artery disease with omega-3 fatty acids.
487558 - Ventricular ectopic beats and their relation to sudden and nonsudden cardiac death afte...
6696138 - Measurement of myocardial contractility in conscious rabbits.
23103608 - The impact of drug eluting stents availability on the treatment choice among medical th...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology journal     Volume:  20     ISSN:  1897-5593     ISO Abbreviation:  Cardiol J     Publication Date:  2013  
Date Detail:
Created Date:  2013-04-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101392712     Medline TA:  Cardiol J     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  121-4     Citation Subset:  IM    
Affiliation:
The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, Fujian Province, China. shi_min_yuan@yahoo.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Blood pressure variability: Epidemiological and clinical issues.
Next Document:  Risk factors for bleeding complications in patients undergoing transcatheter aortic valve implantati...