Document Detail

Congenital diaphragmatic hernia repair during whole body hypothermia for neonatal hypoxic ischemic encephalopathy.
MedLine Citation:
PMID:  23190939     Owner:  NLM     Status:  In-Data-Review    
Major malformations, surgery and persistent pulmonary hypertension (PHT) have been considered contraindications to therapeutic hypothermia (TH) in newborns with hypoxic-ischemic encephalopathy (HIE). We report two patients with undiagnosed congenital diaphragmatic hernia (CDH) who developed HIE after birth. Diagnosis of moderate HIE was formulated based on clinical, laboratory and electroencephalographic criteria. The patients were treated with whole body hypothermia (33.5 °C) for 72 h. During hypothermia the patients underwent surgical repair with regular perioperative course. Ventilatory support with high-frequency oscillatory ventilation, oxygen requirements and inotropic support remained stable during hypothermia. Serial echocardiographic evaluations did not demonstrate any change in pulmonary pressure values. In our experience TH did not increase the risk of hemodynamic instability, PHT or bleeding. Hypothermia may be considered in patients with HIE and CDH or other surgical conditions with favorable prognosis.
S Buratti; E Lampugnani; P Tuo; A Moscatelli
Related Documents :
15643909 - A surgical conundrum: tessier number 4 cleft.
24246139 - Management of choledocholithiasis in an emergency cohort undergoing laparoscopic cholec...
24426659 - Laparoscopic-assisted enterolithotomy for gallstone ileus.
24455329 - A case report of spontaneous closure of a posttraumatic arterioportal fistula.
24469649 - Mini-laparoscopic live donor nephrectomy: initial series.
23015039 - Transcatheter aortic valve replacement and vascular complications definitions.
22586549 - The role of upper gastrointestinal endoscopy in treating postoperative complications in...
15643909 - A surgical conundrum: tessier number 4 cleft.
22524909 - Outcomes in the repair of pilonidal sinus disease excision wounds using a parasacral pe...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  32     ISSN:  1476-5543     ISO Abbreviation:  J Perinatol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  981-4     Citation Subset:  IM    
Department of Neonatal and Pediatric Anesthesia and Intensive Care, Istituto G. Gaslini, Genova, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Ruptured remnant of urachal diverticulum: an unusual cause of congenital urinary ascites.
Next Document:  The APOM polymorphism as a novel risk factor for dyslipidaemia in rheumatoid arthritis: a possible s...