Document Detail

Congenital diaphragmatic hernia: impact of prostanoids in the perioperative period.
MedLine Citation:
PMID:  2221977     Owner:  NLM     Status:  MEDLINE    
A prospective study of 10 neonates with congenital diaphragmatic hernia and five controls to determine the importance of prostanoid concentrations perioperatively and the relation with persistent pulmonary hypertension (PPH) is reported. In neonates with congenital diaphragmatic hernia postoperative concentrations of the vasoconstrictor thromboxane B2 rose significantly and were higher during episodes of PPH; this rise may provoke PPH and subsequent right to left shunting.
A P Bos; D Tibboel; F W Hazebroek; T Stijnen; J C Molenaar
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  65     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-11-07     Completed Date:  1990-11-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  994-5     Citation Subset:  AIM; IM    
Department of Paediatric Surgery, Sophia Children's Hospital, Rotterdam, The Netherlands.
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MeSH Terms
6-Ketoprostaglandin F1 alpha / blood*
Airway Resistance
Hernia, Diaphragmatic / blood,  congenital*,  surgery
Infant, Newborn
Oxygen / blood
Persistent Fetal Circulation Syndrome / blood*,  complications,  surgery
Postoperative Period
Prospective Studies
Respiratory Function Tests
Thromboxane B2 / blood*
Reg. No./Substance:
54397-85-2/Thromboxane B2; 58962-34-8/6-Ketoprostaglandin F1 alpha; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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