Document Detail

Congenital cytomegalovirus infection in 1 twin with a pericardial effusion: a case report.
MedLine Citation:
PMID:  17506373     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Congenital fetal damage related to cytomegalovirus (CMV) infection is largely attributable to maternal primary infection. Twin fetuses may react differently to the same maternal influences. CASE: A woman had a sonographically documented fetal pericardial effusion in 1 twin at 33 weeks of gestation. The workup for maternal infection and fetal structural anomaly was negative except for positive CMV Ige in the maternal serum Cesarean section was performed due to fetal distress. After delivery, CMV viral antigenemia was found in 1 twin with petechiae, thrombocytopenia, hepatosplenomegaly and ventriculomegaly. The other twin was not infected and in stable condition. CONCLUSION: Since twin fetuses simultaneously exposed to the same maternal influence had a completely different outcome, maternal factors play a limited role in influencing CMV transmission.
Fang-Ping Chen; Li-Fen Teng; Ju-Yi Chen; Ning Lee
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  52     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-05-17     Completed Date:  2007-06-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  317-9     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Keelung Chang Gung Memorial Hospital, Taiwan, ROC.
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MeSH Terms
Antibodies, Viral / blood
Cytomegalovirus / immunology
Cytomegalovirus Infections / complications*,  transmission*
Diseases in Twins / congenital,  virology
Infant, Newborn
Infectious Disease Transmission, Vertical*
Pericardial Effusion / congenital*,  virology
Pregnancy Complications, Infectious*
Pregnancy Outcome
Pregnancy, Multiple
Reg. No./Substance:
0/Antibodies, Viral

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