Document Detail

Congenital cystic adenomatoid malformation: is there a difference between the antenatally and postnatally diagnosed cases?
MedLine Citation:
PMID:  15480617     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The majority of congenital cystic adenomatoid malformation (CCAM) lesions are diagnosed antenatally. A few cases however may not be recognised antenatally and present in infancy or later childhood with chest symptoms, including chest infection. OBJECTIVE: To review the clinical and radiological spectrum of CCAM, comparing the antenatally with the postnatally diagnosed cases. MATERIALS AND METHODS: Fifteen cases of antenatally and/or postnatally diagnosed and histopathologically proven CCAM were retrospectively identified over a period of 4 years. Clinical notes, chest radiograph and chest CT were reviewed in all cases. RESULTS: Nine patients were diagnosed antenatally and six postnatally. All antenatally diagnosed patients were asymptomatic at birth, six remained asymptomatic until they had elective surgery and the remaining three developed symptoms before the age of 2 years. In the postnatally diagnosed group, one patient was symptomatic at birth and one patient presented at 16 years; the remaining four presented before the age of 2 years. Depending on the type of lesion, we recognised five radiographic patterns of CCAM. CCAM lesions were classified as CT Stocker type I in seven cases, type II in seven cases and type III in one case. CONCLUSIONS: No significant difference was found between the two groups. Recognition of these lesions antenatally would benefit patients by avoiding delay in making the diagnosis, which can lead to serious complications. CT was successful in accurately diagnosing and grading CCAM lesions.
Mohamed I Tawil; David W Pilling
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2004-10-08
Journal Detail:
Title:  Pediatric radiology     Volume:  35     ISSN:  0301-0449     ISO Abbreviation:  Pediatr Radiol     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-02-04     Completed Date:  2005-07-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  79-84     Citation Subset:  IM    
Department of Radiology, Royal Liverpool Children's Hospital Alder Hey, Eaton Road, West Derby L12 2AP, UK.
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MeSH Terms
Child, Preschool
Cystic Adenomatoid Malformation of Lung, Congenital / diagnosis*,  radiography
Infant, Newborn
Postnatal Care
Prenatal Diagnosis
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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