Document Detail


Congenital cystic adenomatoid malformation connected to an extralobar pulmonary sequestration in the contralateral chest: common origin?
MedLine Citation:
PMID:  15300558     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Extralobar pulmonary sequestration (ELS) and congenital cystic adenomatoid malformation have been reported to coexist in several variations. This suggests a common embryologic origin. A 6-month-old boy presented with a history of recurrent pneumonias. The patient was diagnosed with a right lower lobe congenital cystic adenomatoid malformation (CCAM) and a left lower lobe ELS/CCAM. The diagnosis was made with the aid of a multidetector computed tomography (CT). Three-dimensional CT reconstruction showed the presence of a right lower lobe CCAM, a left lower ELS with an aberrant arterial supply from the celiac axis, and possible venous drainage into the right CCAM. The patient underwent a right thoracotomy. Intraoperatively, the lesions were discovered to be connected by a band of tissue. The right lower lobe CCAM and the left ELS were removed from the right chest. Histologic analysis confirmed the presence of a CCAM within the right lower lobe. The ELS had involvement of a type II CCAM within the sequestration. The connection between the right CCAM and left ELS/CCAM showed an anomalous conducting airway, anomalous vein, and anomalous artery connecting the 2 lesions. The authors present the first case of a CCAM connected to an ELS/CCAM in the contralateral hemithorax. The unique anatomic configuration of these lesions suggests a common embryologic origin of ELS and CCAM.
Authors:
Sean E McLean; John D Pfeifer; Marilyn J Siegel; Eric R Jensen; Pamela M Schuler; Russel Hirsch; George B Mychaliska
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  39     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-08-09     Completed Date:  2005-04-14     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e13-7     Citation Subset:  IM    
Affiliation:
Department of Surgery, Washington University School of Medicine, St Louis, MO, USA.
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MeSH Terms
Descriptor/Qualifier:
Bronchopulmonary Sequestration / embryology*,  radiography,  surgery
Cystic Adenomatoid Malformation of Lung, Congenital / embryology*,  radiography,  surgery
Humans
Imaging, Three-Dimensional
Infant
Infant, Newborn
Lung / blood supply,  embryology
Male
Mesoderm / physiology
Models, Biological
Pneumonia / etiology
Recurrence
Respiratory Distress Syndrome, Newborn / etiology
Thoracotomy
Tomography, Spiral Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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