| Congenital cutaneous candidiasis associated with respiratory distress and elevation of liver function tests: a case report and review of the literature. | |
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MedLine Citation:
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PMID: 9366843 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe congenital cutaneous candidiasis (CCC) in a term newborn. The mother had candidal vaginitis 1 week before delivery. At birth, the infant had a generalized, intensely erythematous, papulovesicular eruption, respiratory distress and elevation of liver function tests. The child responded well to intravenous amphotericin B plus topical and oral nystatin. There have been 13 previously reported cases of CCC in infants weighing more than 1500 gm who had evidence of systemic infection. Two deaths were attributed to candidal pneumonia and sepsis. The majority of infants with CCC have infection localized to the skin, but if there is any evidence of respiratory distress or signs of sepsis the possibility of systemic candidiasis and the need for parenteral antifungal therapy must be considered. |
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Authors:
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B F Cosgrove; K Reeves; D Mullins; M J Ford; F A Ramos-Caro |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Journal of the American Academy of Dermatology Volume: 37 ISSN: 0190-9622 ISO Abbreviation: J. Am. Acad. Dermatol. Publication Date: 1997 Nov |
Date Detail:
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Created Date: 1997-11-26 Completed Date: 1997-11-26 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 7907132 Medline TA: J Am Acad Dermatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 817-23 Citation Subset: IM |
Affiliation:
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Division of Dermatology and Cutaneous Surgery, University of Florida College of Medicine, Gainesville, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amphotericin B
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administration & dosage Antifungal Agents / administration & dosage Candidiasis / transmission Candidiasis, Cutaneous / congenital*, diagnosis*, drug therapy Candidiasis, Vulvovaginal Drug Therapy, Combination / administration & dosage Female Humans Infant, Newborn Infectious Disease Transmission, Vertical Liver Function Tests Nystatin / administration & dosage Pregnancy Pregnancy Complications, Infectious Respiratory Distress Syndrome, Newborn / etiology* |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents; 1397-89-3/Amphotericin B; 1400-61-9/Nystatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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