| Congenital aortic valve disease with rupture of mitral chordae tendineae. | |
| | |
MedLine Citation:
|
PMID: 973889 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A new clinical entity is described in which free aortic regurgitation from congenital aortic valve disease caused rupture of the chordae to the anterior leaflet of the mitral valve in 7 men aged 45 to 63 years (mean 52 years); 2 of the patients also had rupture of chordae to the posterior leaflet. Comparing these patients with those with ruptured mitral chordae in association with rheumatic heart disease and patients with spontaneous chordal rupture, differences were evident. No patient had a history of rheumatic fever and none had active infection. The typical clinical presentation was of acute mitral regurgitation into a small left atrium, with severe pulmonary oedema which was often resistant to medical treatment. The cause of chordal rupture in these patients was in part the result of progressive left ventricular dilatation, of direct trauma to the anterior cusp of the mitral valve, and possibly of a genetic factor. The anatomical features of both aortic and mitral valves are described, and in 3 histology of the mitral valve was available; 2 had myxomatous degeneration similar to that seen in patients with spontaneous chordal rupture, and in 1 there was degeneration of collagen tissue. All patients were treated surgically but the mortality was high (5 out of 7,70%). Early operation with replacement of the aortic and mitral valves is recommended if this high mortality is to be reduced. |
| | |
Authors:
|
S Joseph; R Emanuel; M Sturridge; E Olsen |
Related Documents
:
|
18765969 - Multiple angiomatous mitral valve cysts leading to floppy mitral valve syndrome. 21366689 - Supernormal diastolic function and role of left atrial myocardial deformation analysis ... 648579 - Clinical and angio- and echocardiographic findings in 45 children with mitral valve pro... 19383639 - On-pump beating heart mitral valve repair in patients with patent bypass grafts and sev... 20299349 - Percutaneous mitral valve repair with the mitraclip system: acute results from a real w... 19643859 - Adult patent ductus arteriosus: successful surgery with mitral valvuloplasty. 15729529 - Aetiopathogenesis and long-term outcome of isolated pontine infarcts. 23438569 - Recurrence of thymoma in the right atrium arising from the coronary sinus. 8346729 - Effect of sotalol on heart rate variability assessed by holter monitoring in patients w... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: British heart journal Volume: 38 ISSN: 0007-0769 ISO Abbreviation: Br Heart J Publication Date: 1976 Jul |
Date Detail:
|
Created Date: 1976-12-23 Completed Date: 1976-12-23 Revised Date: 2008-11-20 |
Medline Journal Info:
|
Nlm Unique ID: 0370634 Medline TA: Br Heart J Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 665-73 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aortic Valve
/
pathology Aortic Valve Insufficiency / congenital*, pathology Chordae Tendineae* Humans Male Middle Aged Mitral Valve / pathology Mitral Valve Insufficiency* / etiology* Rupture, Spontaneous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pathology of acute myocardial infarction with particular reference to occlusive coronary thrombi.
Next Document: Endocardial cushion defects: an anatomical study of 54 specimens.