Document Detail

Congenital anomaly of the inferior vena cava and factor V Leiden mutation predisposing to deep vein thrombosis.
MedLine Citation:
PMID:  25395858     Owner:  NLM     Status:  In-Data-Review    
A previously healthy 21-year-old man presented with back pain, bilateral extremity pain, and right lower extremity weakness, paresthesias, and swelling. Sonographic examination revealed diffuse deep vein thrombosis (DVT) in the femoral and popliteal venous system. CT imaging revealed hypoplasia of the hepatic inferior vena cava (IVC) segment with formation of multiple varices and collateral veins around the kidneys. Hematologic workup also discovered a factor V Leiden mutation, further predisposing the patient to DVT. The rare, often overlooked occurrence of attenuated IVC, especially in the setting of hypercoagulable state, can predispose patients to significant thrombosis.
Brooke M Lamparello; Cameron R Erickson; Arun Kulthia; Vasudev Virparia; Zeyar Thet
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Publication Detail:
Type:  Journal Article     Date:  2014-11-04
Journal Detail:
Title:  Vascular health and risk management     Volume:  10     ISSN:  1178-2048     ISO Abbreviation:  Vasc Health Risk Manag     Publication Date:  2014  
Date Detail:
Created Date:  2014-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101273479     Medline TA:  Vasc Health Risk Manag     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  609-13     Citation Subset:  IM    
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