| Congenital anomalies in newborns of women with type 1 diabetes: nationwide population-based study in Norway, 1999-2004. | |
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MedLine Citation:
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PMID: 20929418 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: To estimate the risk of congenital anomalies in offspring of women with type 1 diabetes in Norway during recent years. DESIGN: Nationwide population-based study using the Medical Birth Registry of Norway and the Norwegian type 1 Diabetes Registry. SETTING: All birth clinics in Norway. PARTICIPANTS: All births in Norway during 1999-2004 (N = 350,961), of which 1,583 were births by a mother registered with pregestational type 1 diabetes. MAIN OUTCOME MEASURE: Congenital anomalies, excluding minor anomalies according to the EUROCAT system. RESULTS: Anomalies were registered in 5.7% of offspring of women with type 1 diabetes, and in 2.9% among the background population (odds ratio 2.1, 95% CI: 1.7-2.6). Cardiovascular anomalies were registered in 3.2% in the diabetes group and 0.94% in the background population (odds ratio 3.5, 95% CI: 2.7-4.7). Results were similar when restricted to women identified with type 1 diabetes through the Diabetes Registry. CONCLUSIONS: Women in Norway with type 1 diabetes experience a significantly higher risk of congenital anomalies in their babies compared with the background population. |
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Authors:
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Ingvild Eidem; Lars C Stene; Tore Henriksen; Kristian F Hanssen; Siri Vangen; Stein E Vollset; Geir Joner |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-10-08 |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: 89 ISSN: 1600-0412 ISO Abbreviation: Acta Obstet Gynecol Scand Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: England |
Other Details:
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Languages: eng Pagination: 1403-11 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Oslo University Hospital Ullevål, University of Oslo, Norway. Ingvild.eidem@fhi.no |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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