Document Detail


Congenital agenesis of internal carotid artery with ipsilateral Horner presenting as focal neurological symptoms.
MedLine Citation:
PMID:  21339912     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Internal carotid artery (ICA) agenesis is a rare developmental anomaly and is most frequently asymptomatic, but it may also present as cerebrovascular accidents. The association with Horner's syndrome is exceptional. We present three cases of agenesis of ICA associated with Horner's syndrome and hypochromia iridum presenting as focal neurological symptoms. A system of collaterals develops as a consequence of agenesis of the ICA, making the majority of cases asymptomatic. Three types of collateral circulations have been described. These collaterals increase the risk of aneurysm formation and the occurrence of life-threatening subarachnoid hemorrhages. The association of congenital Horner's syndrome and hypochromia iridum without anhidrosis is highly suggestive of sympathetic pathway injury early in life. Such signs should prompt further diagnostic evaluation to demonstrate the presence of the agenesis of the carotid canal. Early diagnosis is essential to rule out potentially life-threatening associated vascular anomalies.
Authors:
Wassim Farhat; Rechdi Ahdab; Hassan Hosseini
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2011-01-26
Journal Detail:
Title:  Vascular health and risk management     Volume:  7     ISSN:  1178-2048     ISO Abbreviation:  Vasc Health Risk Manag     Publication Date:  2011  
Date Detail:
Created Date:  2011-02-22     Completed Date:  2011-06-13     Revised Date:  2011-07-25    
Medline Journal Info:
Nlm Unique ID:  101273479     Medline TA:  Vasc Health Risk Manag     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  37-40     Citation Subset:  IM    
Affiliation:
Service de Neurologie, Hôpital Henri Mondor, APHP, Faculté de Médecine, Université Paris XII, Créteil, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Carotid Artery, Internal / abnormalities*,  physiopathology
Cerebral Angiography / methods
Cerebrovascular Circulation
Collateral Circulation
Female
Horner Syndrome / complications*,  physiopathology
Humans
Magnetic Resonance Angiography
Male
Regional Blood Flow
Stroke / diagnosis,  etiology*,  physiopathology
Tomography, X-Ray Computed
Vascular Malformations / complications*,  diagnosis,  physiopathology
Young Adult
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