| Congenital adrenal hyperplasia and luteal dysfunction. | |
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MedLine Citation:
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PMID: 2868937 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of 21-hydroxylase deficiency diagnosed and first treated at the age of 3 years is presented. Although pubertal development was delayed, full reproductive function was attained, with menses occurring at 14-33-day intervals. Infertility evaluation at age 20 revealed elevated 17-hydroxyprogesterone (17Po) and androgen concentrations and reduced luteal phase progesterone levels consistent with inadequate luteal function. This was corrected with additional corticosteroid replacement. Normal pregnancy and delivery followed. |
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Authors:
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A L Villanueva; R W Rebar |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Volume: 23 ISSN: 0020-7292 ISO Abbreviation: Int J Gynaecol Obstet Publication Date: 1985 Dec |
Date Detail:
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Created Date: 1986-03-28 Completed Date: 1986-03-28 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0210174 Medline TA: Int J Gynaecol Obstet Country: IRELAND |
Other Details:
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Languages: eng Pagination: 449-54 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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17-alpha-Hydroxyprogesterone Adrenal Hyperplasia, Congenital* / complications, drug therapy, physiopathology* Adult Androgens / blood Female Humans Hydrocortisone / therapeutic use Hydroxyprogesterones / blood Infertility, Female / etiology Luteal Phase* Pregnancy Steroid Hydroxylases / deficiency* |
| Grant Support | |
ID/Acronym/Agency:
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HD-12303/HD/NICHD NIH HHS; HD-19542/HD/NICHD NIH HHS; RR-00827/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Androgens; 0/Hydroxyprogesterones; 50-23-7/Hydrocortisone; 68-96-2/17-alpha-Hydroxyprogesterone; EC 1.14.-/Steroid Hydroxylases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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