| Congenital acute lymphoblastic leukemia: a two-case report and a review of the literature. | |
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MedLine Citation:
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PMID: 21046414 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Congenital leukemia is a rare disease with particular biological and clinical characteristics which differs from those of older children and adults. Here, we describe two cases of congenital acute lymphoblastic leukemia in two newborns with different clinical presentations (leukemia cutis vs. splenomegaly and respiratory distress) and fatal outcome. Both cases shared the expression of myeloid antigens (CD65) and cytogenetic disorders involving the MLL gene (location 11q23) which are associated to extremely poor prognosis. |
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Authors:
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Ma Pilar Bas Suárez; Jezabel López Brito; Candelaria Santana Reyes; Manuel Gresa Muñoz; Rosario Diaz Pulido; Jose Carlos Lodos Rojas |
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Publication Detail:
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Type: Journal Article Date: 2010-11-03 |
Journal Detail:
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Title: European journal of pediatrics Volume: 170 ISSN: 1432-1076 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: Germany |
Other Details:
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Languages: eng Pagination: 531-4 Citation Subset: IM |
Affiliation:
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Department of Neonatology, University Hospital Maternity Ward of the Canary Islands, Las Palmas, Spain, pilybas@yahoo.es. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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