Document Detail


Congenital Trypanosoma cruzi infection. Efficacy of its monitoring in an urban reference health center in a non-endemic area of Argentina.
MedLine Citation:
PMID:  20439964     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Congenital transmission (CT) has acquired relevance in Chagas disease (CHD). A cohort of pregnant CHD women (4,355) and their babies were studied in the period 1994-2004. Children were excluded when they had received blood transfusions, or were born or had been in endemic areas; CT rate was 6.1%. Babies were diagnosed between months 1 and 5 in 68.9% of the cases and between months 6 and 12 in 31.1%. In the latter group, parasitemia was detected in 94% and serology in 74.7%. Between months 6 and 9, parasitemia diagnosed 36.2% (P = 0.000) more cases than serology. If serology had been the diagnosis method, those children would have been considered CT free. Taking the overall outcomes, 38.1% of babies were CT free, and 55.8% did not complete the follow-up. Establishing CT as a public health priority and improving first-line health service, congenital CHD coverage could be more efficient in endemic countries.
Authors:
Ana María De Rissio; Adelina Rosa Riarte; Miriam Martín García; Mónica Inés Esteva; Marta Quaglino; Andrés Mariano Ruiz
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  82     ISSN:  1476-1645     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-04     Completed Date:  2010-05-27     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  838-45     Citation Subset:  AIM; IM    
Affiliation:
Instituto Nacional de Parasitología Dr. Mario Fatala Chaben, ANLIS Dr. Carlos G Malbran, Buenos Aires, Argentina. amderissio@yahoo.com.ar
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Antibodies, Protozoan / blood
Argentina / epidemiology
Chagas Disease / congenital*,  epidemiology
Female
Humans
Infant
Infant, Newborn
Population Surveillance
Pregnancy
Pregnancy Complications, Parasitic / epidemiology*
Seroepidemiologic Studies
Time Factors
Trypanosoma cruzi* / immunology
Urban Population*
Chemical
Reg. No./Substance:
0/Antibodies, Protozoan
Comments/Corrections
Erratum In:
Am J Trop Med Hyg. 2010 Jun;82(6):1202

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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