Document Detail

Congenital syphilis: early- and late-stage findings of rhagades and dental anomalies.
MedLine Citation:
PMID:  21133996     Owner:  NLM     Status:  In-Data-Review    
Congenital syphilis occurs via vertical transmission when Treponema pallidum crosses the placenta after the 16th week of gestation. Manifestations of congenital syphilis vary from asymptomatic infection to stillbirth. We present a case of congenital syphilis in a Vietnamese orphan who presented with rhagades, hearing deficit, and abnormal dentition after adoption in the United States. He demonstrated both early- and late-stage findings of congenital syphilis. He is presumed to be 5 years old, and it is uncertain if he received treatment. Upon arrival to the United States, his rapid plasma reagin test was negative, but his fluorescent treponemal antibody-absorption test was positive, so no further treatment was recommended. It is possible that other late congenital syphilis stigmata may develop in his later years. The Centers for Disease Control recommends screening all pregnant women for syphilis at the beginning of prenatal care. Clinicians should be made aware of the manifestations of congenital syphilis, especially when caring for international orphans and children born to mothers who lacked prenatal care.
Shilpi Khetarpal; Ellen Kempf; Eliot Mostow
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Publication Detail:
Type:  Journal Article     Date:  2010-12-07
Journal Detail:
Title:  Pediatric dermatology     Volume:  28     ISSN:  1525-1470     ISO Abbreviation:  Pediatr Dermatol     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  401-3     Citation Subset:  IM    
Copyright Information:
© 2010 Wiley Periodicals, Inc.
Northeastern Ohio Universities College of Medicine, Rootstown, Ohio Department of Pediatrics, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio Department of Dermatology, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio.
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