| Congenital Langerhans Cell Histiocytosis with Placental Involvement. | |
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MedLine Citation:
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PMID: 23432454 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Congenital presentations of Langerhans cell histiocytosis (LCH) are exceedingly rare and concurrent placental parenchymal involvement has not been definitively documented in the literature. We present two cases of congenital MS-LCH with placental involvement resembling chronic villitis. Placental examination may provide the initial diagnostic evidence of LCH and may significantly influence patient management and outcome; however, the prognostic implications remain unclear. In a clinical context suspicious for congenital LCH, the observation of chronic villitis should prompt consideration of placental involvement by LCH. |
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Authors:
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Jefferson Terry; Francesca Pluchinotta; Stephen Sanders; Jo-Anne Vergilio; Scott Hyde; Theonia K Boyd |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-2-22 |
Journal Detail:
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Title: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society Volume: - ISSN: 1093-5266 ISO Abbreviation: Pediatr. Dev. Pathol. Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-2-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9809673 Medline TA: Pediatr Dev Pathol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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a McMaster Children's Hospital, Pathology and Molecular Medicine. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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