Document Detail


Congenital Horner's syndrome.
MedLine Citation:
PMID:  7387512     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Patients with congenital Horner's syndrome (who seemed, on the basis of their clinical history and the distribution fo anhidrosis, to have a preganglionic lesion) had partial mydriatic failure with hydroxyamphetamine hydrobromide and a supersensitivity to phenylephrine hydrochloride. This apparent paradox can be readily explained by postulating an aorthograde transsynaptic dysgenesis of the postganglionic neuron, such as has been demonstrated in the sympathetic nervous system of newborn animals. The failure of hydroxyamphetamine to cause mydriasis indicates damage to the postganglionic sympathetic neuron, but in the neonate this damage may be secondary to a preganglionic lesion.
Authors:
J M Weinstein; T J Zweifel; H S Thompson
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of ophthalmology     Volume:  98     ISSN:  0003-9950     ISO Abbreviation:  Arch. Ophthalmol.     Publication Date:  1980 Jun 
Date Detail:
Created Date:  1980-08-15     Completed Date:  1980-08-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7706534     Medline TA:  Arch Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1074-8     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Eye Color
Face / blood supply
Horner Syndrome / congenital*,  physiopathology
Humans
Infant
Male
Middle Aged
Sympathetic Nervous System / injuries,  physiopathology
Vasodilation
Visual Pathways / injuries,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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