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A Congenital Case of Circumscribed Acral Hypokeratosis.
MedLine Citation:
PMID:  21692836     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
  Circumscribed acral hypokeratosis is a disorder characterized by areas of erythematous depressed skin with distinct histopathological findings typically found on the palmar and plantar surfaces. Most patients are middle-aged women who report a multiyear history. We present an 10-year-old African American boy who had an asymptomatic, irregularly shaped erythematous lesion on his left medial foot that had been present since birth. A biopsy showed an abrupt, well-demarcated decrease in the thickness of the stratum corneum layer, with no parakeratosis, that was consistent with a diagnosis of circumscribed hypokeratosis. This represents the first pediatric and congenital case of circumscribed hypokeratosis reported. We review the literature and discuss the ramifications of a congenital case on understanding the etiology of circumscribed hypokeratosis.
Authors:
Joshua Arbesman; Lesley C Loss; Klaus F Helm; Ilene L Rothman
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-22
Journal Detail:
Title:  Pediatric dermatology     Volume:  -     ISSN:  1525-1470     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 Wiley Periodicals, Inc.
Affiliation:
Department of Dermatology, School of Medicine and Biomedical Sciences, University of Buffalo, Buffalo, New York Department of Dermatology, College of Medicine, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, Pennsylvania Department of Dermatology, Women and Childrens' Hospital of Buffalo, Buffalo, New York.
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