Document Detail


Conformation-dependent chemical reaction of formic acid with an oxygen atom.
MedLine Citation:
PMID:  19569616     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Conformation dictates many physical and chemical properties of molecules. The importance of conformation in the selectivity and function of biologically active molecules is widely accepted. However, clear examples of conformation-dependent bimolecular chemical reactions are lacking. Here we consider a case of formic acid (HCOOH) that is a valuable model system containing the -COOH carboxyl functional group, similar to many biomolecules including the standard amino acids. We have found a strong case of conformation-dependent reaction between formic acid and atomic oxygen obtained in cryogenic matrices. The reaction surprisingly leads to peroxyformic acid only from the ground-state trans conformer of formic acid, and it results in the hydrogen-bonded complex for the higher-energy cis conformer.
Authors:
Leonid Khriachtchev; Alexandra Domanskaya; Kseniya Marushkevich; Markku Räsänen; Bella Grigorenko; Alexander Ermilov; Natalya Andrijchenko; Alexander Nemukhin
Related Documents :
10995286 - Kinetics of interaction of vanillin with amino acids and peptides in model systems.
7391216 - Formation of electron-capturing derivatives of alprenolol by transboronation: applicati...
17020336 - Bidirectional synthesis of the central amino acid of chloptosin.
22010236 - Comparison of amino acid digestibility of feedstuffs determined with the precision-fed ...
6642196 - Changes induced by gramoxon in tissue phospholipids and phospholipid fatty acids in mou...
25380546 - New insight into deactivation of commercial scr catalyst by arsenic: an experiment and ...
Publication Detail:
Type:  Letter; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The journal of physical chemistry. A     Volume:  113     ISSN:  1520-5215     ISO Abbreviation:  J Phys Chem A     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-17     Completed Date:  2009-09-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9890903     Medline TA:  J Phys Chem A     Country:  United States    
Other Details:
Languages:  eng     Pagination:  8143-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Absorption
Formic Acids / chemistry*
Hydrogen Bonding
Models, Molecular
Molecular Conformation*
Oxygen / chemistry*
Spectroscopy, Fourier Transform Infrared
Stereoisomerism
Chemical
Reg. No./Substance:
0/Formic Acids; 64-18-6/formic acid; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Relaxation of NH(a(1)Delta, v = 1) in Collisions with H((2)S): An Experimental and Theoretical Study...
Next Document:  Demixing Transition of the Aqueous Solution of Amyloidogenic Peptides: A REMD Simulation Study.