Document Detail


Confluent hepatic fibrosis in advanced cirrhosis: evaluation with MR imaging.
MedLine Citation:
PMID:  8234718     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To assess the usefulness of magnetic resonance (MR) imaging in diagnosis of confluent fibrosis in patients with advanced cirrhosis. MATERIALS AND METHODS: Findings on pretransplantation MR images were compared with findings on pretransplantation computed tomographic (CT) scans and posttransplantation gross appearance and histologic findings in 11 patients with confluent fibrosis. In all patients, MR imaging was performed before and after administration of gadopentetate dimeglumine. RESULTS: Nine lesions appeared wedge shaped and involved the medial segment of the left lobe, anterior segment of the right lobe, or both; two lesions consisted entirely of lobar or segmental fibrosis. Associated volume loss in the affected regions was seen in 10 lesions. All 11 lesions were hypoattenuating on non-contrast material-enhanced CT scans. CONCLUSION: Findings on MR images corresponded well to CT findings and gross appearance. MR imaging provided useful morphologic information about confluent fibrosis, but the MR signal characteristics are not unique and do not enable differentiation from hepatic neoplasms.
Authors:
K Ohtomo; R L Baron; G D Dodd; M P Federle; Y Ohtomo; S R Confer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Radiology     Volume:  189     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1993-12-17     Completed Date:  1993-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  871-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, Presbyterian University Hospital, Pittsburgh, PA 15213.
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MeSH Terms
Descriptor/Qualifier:
Contrast Media
Diagnosis, Differential
Drug Combinations
Female
Gadolinium / diagnostic use
Gadolinium DTPA
Humans
Liver / pathology*
Liver Cirrhosis / diagnosis*
Liver Neoplasms / diagnosis
Magnetic Resonance Imaging
Male
Meglumine / diagnostic use
Middle Aged
Organometallic Compounds / diagnostic use
Pentetic Acid / analogs & derivatives,  diagnostic use
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Drug Combinations; 0/Organometallic Compounds; 6284-40-8/Meglumine; 67-43-6/Pentetic Acid; 7440-54-2/Gadolinium; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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