Document Detail

Confirmation for a delayed inhibition of return by systematic sampling in schizophrenia.
MedLine Citation:
PMID:  20064665     Owner:  NLM     Status:  MEDLINE    
Inhibition of return (IOR) is a phenomenon thought to reflect a mechanism to protect the organism from redirecting attention to previously scanned insignificant locations. A number of studies reported altered IOR in schizophrenia patients with a reduction of its amplitude. However, incomplete sampling of stimulus onset asynchronies (SOAs) makes data on IOR time course incomplete. We examined 14 stabilized young patients with recent onset schizophrenia and 16 healthy controls matched for gender, age, and years of education. Schizophrenia patients (13 males, 1 female) had a mean age of 26.3+/-5.8 years and a mean number of years of study of 9.6+/-3.6. Their illness had a mean duration of 147 weeks. Patients displayed moderate overall slow reaction times (387 ms) in comparison with controls (322 ms). Onset of IOR was found to be delayed in schizophrenia patients appearing between 700 and 800 ms following the cue onset while it appeared at 300 ms in controls. In patients, IOR was constant up to 1100 ms; however, its amplitude was weak with an average of 6 ms. Validity effects (overall and at each SOA value) were uncorrelated to age, years of study, duration of illness, or total or subscale scores on the Positive and Negative Syndrome Scale.
Oussama Kebir; Olfa Ben Azouz; Yasmine Rabah; Lamia Dellagi; In?s Johnson; Isabelle Amado; Karim Tabbane
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-01-12
Journal Detail:
Title:  Psychiatry research     Volume:  176     ISSN:  0165-1781     ISO Abbreviation:  Psychiatry Res     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-22     Completed Date:  2010-04-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911385     Medline TA:  Psychiatry Res     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  17-21     Citation Subset:  IM    
Copyright Information:
Copyright 2008 Elsevier Ltd. All rights reserved.
Research unit Cognitive dysfunctions in psychiatric diseases UR 02/04, Department of Psychiatry B, Razi Hospital, 2010 La Manouba, Tunisia.
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MeSH Terms
Analysis of Variance
Attention / physiology*
Case-Control Studies
Inhibition (Psychology)*
Photic Stimulation / methods
Reaction Time / physiology*
Reproducibility of Results
Schizophrenia / physiopathology*
Schizophrenic Psychology*
Time Factors
Visual Fields / physiology
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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