Document Detail


Concurrent variations of cerebral blood flow and arterial blood pressure in simulated sleep apnea.
MedLine Citation:
PMID:  22255022     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Obstructive Sleep Apnea (OSA) is one of the most common sleep disordered breathing which affects about 15 % of US adult population. OSA is considered to be an important risk factor for the development of cardiac dysfunction and stroke. In this paper, we present the initial results of our investigation of the relationship between arterial blood pressure and cerebral blood flow velocity in simulated apnea. Sixteen healthy subjects (9 male, 7 female) of 29±4.89 yrs age and body mass index of 24.07±4.84 kg/m(2) participated in the study. Our findings indicate that cerebral blood flow velocity variations has a relatively high correlation to changes in blood pressure during simulated apnea (r=0.74 ±0.06), suggesting that cerebral autoregulation may not compensate for the pressure changes during apnea.
Authors:
Raichel Alex; Gauri Bhave; Mohammad A Al-Abed; Aditya Bashaboyina; Swathi Iyer; Donald E Watenpaugh; Rong Zhang; Khosrow Behbehani
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference     Volume:  2011     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2012-01-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3209-12     Citation Subset:  IM    
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