| Concurrent myocardial and cerebral infarctions after intranasal cocaine use. | |
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MedLine Citation:
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PMID: 1542908 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: Cardiac and cerebrovascular complications associated with cocaine abuse have increasingly been reported, but concurrent development of cocaine-induced cardiac disease and stroke has rarely been reported. CASE DESCRIPTION: A 37-year-old man with a remote history of intravenous heroin and amphetamine use, cardiomyopathy, and recent cocaine use developed chest pain and ventricular tachycardia 30 minutes after intranasal cocaine hydrochloride use and jogging on a cold winter morning. Ventricular tachycardia was converted to atrial fibrillation. He was proven to have a small myocardial infarction. Within 6 hours of cocaine use he suffered a left hemisphere stroke. Cardiac electrophysiologic evaluation revealed inducible ventricular tachycardia. CONCLUSIONS: To our knowledge, this is the first report of concurrent myocardial infarction, life-threatening ventricular arrhythmias, and cerebral infarction temporally related to cocaine use. It is probable that one mechanism by which cocaine use causes stroke is to trigger expression of a known cardiac source of embolism. |
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Authors:
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M A Sloan; T A Mattioni |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Stroke; a journal of cerebral circulation Volume: 23 ISSN: 0039-2499 ISO Abbreviation: Stroke Publication Date: 1992 Mar |
Date Detail:
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Created Date: 1992-04-08 Completed Date: 1992-04-08 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0235266 Medline TA: Stroke Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 427-30 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Maryland School of Medicine, Baltimore. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Intranasal Adult Cerebral Infarction / chemically induced*, complications Cocaine / adverse effects* Cold Temperature Humans Jogging Male Myocardial Infarction / chemically induced*, complications |
| Chemical | |
Reg. No./Substance:
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50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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