Document Detail

Concurrent micronutrient deficiencies in lactating mothers and their infants in Indonesia.
MedLine Citation:
PMID:  11273854     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Deficiencies of vitamin A, iron, and zinc are prevalent worldwide, affecting vulnerable groups such as lactating women and infants. However, the existence of concurrent deficiencies has received little attention. OBJECTIVE: The aim was to investigate the extent to which deficiencies of vitamin A, iron, and zinc coexist and the nutritional relation between lactating mothers and their infants. DESIGN: In a cross-sectional survey in rural West Java, Indonesia, 155 lactating mothers and their healthy infants were assessed anthropometrically and blood, urine, and breast-milk samples were obtained. RESULTS: Marginal vitamin A deficiency was found in 54% of the infants and 18% of the mothers. More than 50% of the mothers and infants were anemic and 17% of the infants and 25% of the mothers were zinc deficient. There was a strong interrelation between the micronutrient status of the mothers and infants and the concentrations of retinol and beta-carotene in breast milk. Vitamin A deficiency in infants led to an increased risk of anemia and zinc deficiency (odds ratios: 2.5 and 2.9, respectively), whereas in mothers the risk of anemia and iron deficiency (odds ratios: 3.8 and 4.8, respectively) increased. In infants, concentrations of insulin-like growth factor I were related to concentrations of plasma retinol and beta-carotene but not to zinc. CONCLUSIONS: Micronutrient deficiencies were prevalent in West Java. The micronutrient status of lactating mothers and that of their infants were closely related; breast milk was a key connecting factor for vitamin A status. Furthermore, concurrent micronutrient deficiencies appeared to be the norm.
M A Dijkhuizen; F T Wieringa; C E West; Muherdiyantiningsih; Muhilal
Related Documents :
16756354 - Evaluation of the simultaneous effects of processing parameters on the iron and zinc so...
12000914 - Identification of iron sulphide grains in protoplanetary disks.
11382544 - Zinc and iron bioavailability in a powder or in-bottle-sterilized infant formula estima...
9349444 - Prevalence of anaemia in pregnant women during the last trimester.
3127574 - Surfactant can be supplemented before the neonate needs it.
17139894 - Parastomal hernia repair--bielañski hospital experience.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  73     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-03-29     Completed Date:  2001-04-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  786-91     Citation Subset:  AIM; IM    
Division of Human Nutrition and Epidemiology, Wageningen University, Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anemia, Iron-Deficiency / epidemiology
Cross-Sectional Studies
Indonesia / epidemiology
Insulin-Like Growth Factor I / analysis
Iron / analysis*,  deficiency
Lactation / blood,  physiology*
Micronutrients / deficiency*
Milk, Human / chemistry*
Odds Ratio
Vitamin A / analysis*
Vitamin A Deficiency / epidemiology
Zinc / analysis*,  deficiency
beta Carotene / analysis
Reg. No./Substance:
0/Micronutrients; 11103-57-4/Vitamin A; 67763-96-6/Insulin-Like Growth Factor I; 7235-40-7/beta Carotene; 7439-89-6/Iron; 7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Serum concentrations of beta-carotene and alpha-tocopherol are associated with diet, smoking, and ge...
Next Document:  Intake of major nutrients by women in the Maternal Phenylketonuria (MPKU) Study and effects on plasm...