Document Detail


Concurrence of multiple sclerosis and intracranial glioma. Report of a case and review of the literature.
MedLine Citation:
PMID:  14672509     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a 39-year-old female patient known to have multiple sclerosis (MS), who later developed cerebral glioblastoma. The tumor was documented on the brain-magnetic resonance imaging (MRI) during the work-up for an apparent relapsing MS, and was subsequently confirmed pathologically by stereotactic biopsy and the postmortem brain examination. Our case, as well as others, re-emphasizes the need to evaluate the symptoms and brain MRI carefully, even in well-documented MS subjects. The concurrence of MS and intracranial glioma is uncommon. The possible relationship between the 2 diseases was discussed, and related literature reviewed.
Authors:
S Shuangshoti; G M Hjardermaal; Y Ahmad; J L Arden; M M Herman
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Clinical neuropathology     Volume:  22     ISSN:  0722-5091     ISO Abbreviation:  Clin. Neuropathol.     Publication Date:    2003 Nov-Dec
Date Detail:
Created Date:  2003-12-15     Completed Date:  2004-01-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8214420     Medline TA:  Clin Neuropathol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  304-8     Citation Subset:  IM    
Affiliation:
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. shanop@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adjuvants, Immunologic / therapeutic use
Adult
Astrocytoma / complications*,  pathology,  surgery
Brain Neoplasms / complications*,  pathology,  surgery
Fatal Outcome
Female
Humans
Interferon-beta / therapeutic use
Magnetic Resonance Imaging
Multiple Sclerosis / complications*,  drug therapy
Treatment Outcome
Chemical
Reg. No./Substance:
0/Adjuvants, Immunologic; 145258-61-3/interferon beta 1a; 77238-31-4/Interferon-beta

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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