Document Detail

Concordance of coronary artery calcium estimates between MDCT and electron beam tomography.
MedLine Citation:
PMID:  16304010     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The objective of our study was to compare MDCT with electron beam tomography (EBT) for the quantification of coronary artery calcification (CAC). MATERIALS AND METHODS: Sixty-eight patients underwent both MDCT and EBT within 2 months for the quantification of CAC. The images were scored in a blinded fashion and independently by two observers with a minimum of 7 days between the interpretations of images obtained from one scanner type to the other. RESULTS: Presence versus absence of CAC was discordant by EBT versus MDCT in 6% (n = 4) of the cases by observer 1, with one of these cases also discordant by observer 2. All cases except one (aortic calcium misidentified as CAC) were among those with a mean Agatston score of less than 5 present on EBT but absent on MDCT. EBT and MDCT scores correlated well (r = 0.98-0.99). The relative median variability between EBT and MDCT for the Agatston score was 24% for observer 1 and 27% for observer 2 and was 18% and 14%, respectively, for volume score (average for both observers: 27% for Agatston score and 16% for volume score). Scores were higher for EBT than MDCT in approximately half of the cases, with little systematic difference between the two (median EBT-MDCT difference: Agatston score, -0.55; volume score, 3.4 mm3). The absolute median difference averaged for the two observers was 28.75 for the Agatston score and 15.4 mm3 for the volume score. CONCLUSION: Differences in CAC measurements using EBT and MDCT are similar to interscan differences in CAC measurements previously reported for EBT or for other MDCT scanners individually.
Anthony L Daniell; Nathan D Wong; John D Friedman; Nachum Ben-Yosef; Romalisa Miranda-Peats; Sean W Hayes; Xingping Kang; Maria G Sciammarella; Ling de Yang; Guido Germano; Daniel S Berman
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  185     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-11-23     Completed Date:  2006-01-27     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1542-5     Citation Subset:  AIM; IM    
Department of Imaging, Division of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
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MeSH Terms
Calcinosis / pathology,  radiography*
Coronary Disease / pathology,  radiography*
Image Processing, Computer-Assisted
Middle Aged
Tomography, X-Ray Computed / methods*
Comment In:
AJR Am J Roentgenol. 2005 Dec;185(6):1540-1   [PMID:  16304009 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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