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Conceptual priming in semantic dementia: A window into the cognitive and neural basis of conceptual implicit memory.
MedLine Citation:
PMID:  21049346     Owner:  NLM     Status:  In-Data-Review    
The present study examined the impact of impairment in semantic memory on conceptual repetition priming by means of the longitudinal study of a patient with semantic dementia. ST was tested in four consecutive years, during which his semantic memory progressively deteriorated. On each occasion, he performed an abstract/concrete verification task and a verb generation task. In both of these tasks, performance during a test phase was compared for stimuli previously processed in a study phase and stimuli first seen in the test phase. Control subjects showed priming, as indicated by faster responses to studied than to baseline stimuli. ST showed intact priming that was of normal magnitude in the first two years of testing, but failed to show priming in the subsequent two years of testing. This pattern of results is interpreted with reference to the differential decline of item-specific and superordinate knowledge. The implications of these findings for the neural basis of conceptual priming are also discussed.
Mieke Verfaellie; Kelly S Giovanello
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cognitive neuropsychology     Volume:  23     ISSN:  0264-3294     ISO Abbreviation:  Cogn Neuropsychol     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2010-11-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8411889     Medline TA:  Cogn Neuropsychol     Country:  England    
Other Details:
Languages:  eng     Pagination:  606-20     Citation Subset:  -    
Boston University School of Medicine and Boston VA Healthcare System, Boston, MA, USA.
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