Document Detail


Concept and first experimental results of a new ferromagnetic assist device for extra-aortic counterpulsation.
MedLine Citation:
PMID:  24061069     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVES: Based on a ferromagnetic silicone cuff for extra-aortic counterpulsation, a new assist device concept was developed. The driving force is generated by an external magnetic field, which leads to contraction of a soft magnetic cuff. The force generation capacity of the device was tested in a silicone aorta model.
METHODS: Magnetic elastomers can be constructed through dispersion of micro- or nanoparticles in polymer matrices and were designed to act as soft actuators. Two magnetically active silicone cuffs were produced with a nanomagnet loading of 250 wt% (Cuff 1) and a micromagnet loading of 67 wt% (Cuff 2). The magnetic cuffs were applied on a silicone aorta model and contracted against hydrostatic pressure.
RESULTS: A full contraction of Cuff 1 was possible against a maximal hydrostatic pressure of 30 cmH2O (22 mmHg) at a magnetic flux density of 0.4 T (Tesla) and 65 cmH2O (48 mmHg) at a magnetic flux density of 1.2 T. A 50% contraction of Cuff 2 was possible against a maximal hydrostatic pressure of 80 cmH2O (59 mmHg) at a magnet-cuff-distance (MCD) of 0 cm. At MCDs of 1 and 2 cm a 50% contraction was possible against 33 cmH2O (24 mmHg) and 10 cmH2O (7 mmHg), respectively.
CONCLUSIONS: Combining the advantages of magnetic elastomers with the principle of extra-aortic counterpulsation in a new assist device concept avoids the need for anticoagulation (no contact with bloodstream). With regard to the magnetic principle of action, no intra- to extracorporeal connection is needed. More experimental work is needed to further increase the force generated by the silicone cuff and to transfer the device concept into an in vivo setting.
Authors:
Christoph T Starck; Jakob Becker; Roland Fuhrer; Simon Sündermann; Jan Wendelin Stark; Volkmar Falk
Related Documents :
3216399 - Catecholamine release and potassium accumulation in the isolated globally ischemic rabb...
6198759 - Calcium antagonists and myocardial protection: diltiazem during cardioplegic arrest.
2470359 - Significance of the cardioprotective effect of prostanoids and indomethacin.
1913749 - Reduced prostaglandin release from the stunned porcine heart--significance for attenuat...
23276349 - Deltoid muscle pressures during arthroscopic rotator cuff repair.
8604919 - Age differences in effects of hypothermic ischemia on endothelial and ventricular funct...
23254579 - Losartan/hydrochlorothiazide combination therapy surpasses high-dose angiotensin recept...
1268059 - The pathology of lymphangioma circumscriptum.
7560909 - Effects of stobadine on survival, histopathologic outcome and acid-base status after gl...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-9-22
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  -     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2013 Sep 
Date Detail:
Created Date:  2013-9-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Clinic of Cardiac and Vascular Surgery, University Hospital Zurich, Zurich, Switzerland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Isotopic evidence for continental ice sheet in mid-latitude region in the supergreenhouse Early Cret...
Next Document:  Nocturnal Hypertension or Nondipping: Which Is Better Associated With the Cardiovascular Risk Profil...