| Concept and evaluation of hibernating myocardium. | |
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MedLine Citation:
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PMID: 10073264 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hibernating myocardium is a state of persistently impaired myocardial and left ventricular function at rest due to reduced coronary blood flows. It can be defined as an exquisitely regulated tissue successfully adapting its activity to prevailing circumstances. It has been documented in patients with angina (chronic stable and/or unstable), acute myocardial infarction, heart failure and/or severe left ventricular dysfunction, and anomalous left coronary artery from the pulmonary artery. The diagnosis of hibernating myocardium involves (a) documenting left ventricular dysfunction at rest and (b) documenting that there is viable myocardium in the area of dysfunction. Tests commonly used for the latter are dobutamine echocardiography, 201Tl isotope studies, and positron image tomography. Revascularization, either by surgery or by interventional catheter techniques, has been shown to improve or normalize the abnormal left ventricular function at rest. |
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Authors:
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S H Rahimtoola |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Annual review of medicine Volume: 50 ISSN: 0066-4219 ISO Abbreviation: Annu. Rev. Med. Publication Date: 1999 |
Date Detail:
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Created Date: 1999-04-30 Completed Date: 1999-04-30 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 2985151R Medline TA: Annu Rev Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 75-86 Citation Subset: IM |
Affiliation:
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Griffith Center, LAC + USC Medical Center, University of Southern California 90033, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Physiological Angina Pectoris / complications Angina, Unstable / complications Cardiac Output, Low / complications Chronic Disease Coronary Circulation / physiology Coronary Vessel Anomalies / complications Echocardiography Humans Myocardial Contraction / physiology Myocardial Infarction / complications Myocardial Revascularization Myocardial Stunning / diagnosis, etiology, physiopathology*, therapy Myocardium / pathology Pulmonary Artery / abnormalities Radiopharmaceuticals / diagnostic use Thallium Radioisotopes / diagnostic use Tissue Survival Tomography, Emission-Computed Ventricular Dysfunction, Left / complications Ventricular Function, Left / physiology |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 0/Thallium Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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