| Concentric remodeling detection by magnetocardiography in patients with recent onset arterial hypertension. | |
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MedLine Citation:
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PMID: 15189524 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this work was to evaluate a number of magnetocardiographic (MCG) indices in their predictive ability for left ventricular (LV) concentric remodeling. Twenty-five male patients affected by essential hypertension for no longer than 15 months and presenting signs of LV remodeling participated in the study; 25 normal men volunteers of comparable age were evaluated as controls. All participants underwent echocardiography (ECHO), electrocardiography (ECG), and magnetocardiography (MCG). Several MCG based indices were evaluated, namely the QRS Integral, T Integral, QRS-T Integral, T/QRS Integral, RS Index, and the variations of the electrical cardiac axis (ECA) orientation. MCG indices were compared with ECHO parameters, i.e., left ventricular mass index (LVMI) and relative wall thickness (RWT), and with ECG parameters, i.e., 12-lead standard ECG LVH Sokolow-Lyon and Cornell voltages. QRS Integral values for patients and controls were significantly different (P = 0.03), whereas T Integral values showed only a tendency to differentiate between patients and controls (P = 0.15). No significant correlation between MCG and echocardiographic indices in patients was found; RWT showed a tendency to correlate with QRS Integral (r = 0.34, P = 0.17) and with RS Index (r = 0.49, P = 0.15), and LVMI showed a tendency to correlate with the variations of the ECA orientation (r = 0.38, P = 0.10). Our findings, also supported by preliminary results on patients affected by hypertension induced LV hypertrophy, suggest a potential role of MCG in the evaluation of early electrophysiological alterations due to LV concentric remodeling. |
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Authors:
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Silvia Comani; Sabina Gallina; Antonio Lagatta; Marco Orlandi; Giovanni Morana; Silvano De Luzio; Donatella Brisinda; Raffaele De Caterina; Riccardo Fenici; Gian Luca Romani |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 27 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-06-10 Completed Date: 2004-09-28 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: 709-18 Citation Subset: IM |
Affiliation:
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Institute of Advanced Biomedical Technologies (ITAB), Chieti University, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cardiac Volume / physiology Echocardiography Electrocardiography / instrumentation* Electromagnetic Fields* Female Follow-Up Studies Heart Conduction System / physiopathology Humans Hypertension / complications, physiopathology* Hypertrophy, Left Ventricular / diagnosis, physiopathology* Male Middle Aged Reference Values Sensitivity and Specificity Signal Processing, Computer-Assisted Statistics as Topic Ventricular Remodeling / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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