Document Detail

Concentric left ventricular hypertrophy in patients with Takayasu arteritis.
MedLine Citation:
PMID:  7902037     Owner:  NLM     Status:  MEDLINE    
Although aortic regurgitation (AR) in patients with Takayasu arteritis (TA) is believed to be caused by dilatation of the aortic ring or thickening of the aortic cusps, the pattern of left ventricular hypertrophy (LVH) in these patients has not been described. To clarify the geometry of the LV in patients with TA that had been documented both echocardiographically and hemodynamically, the authors evaluated 22 patients with TA and severe AR (group 1), 10 with TA and systemic hypertension (group 2), and 17 with isolated severe AR of other etiologies (group 3). M-mode echocardiography showed that LV dimensions were smaller in groups 1 and 2 than in group 3 and that wall thickness was greater in group 1 than in group 3. The concentric hypertrophic ratio (CHR = wall thickness/LV end-diastolic dimension+wall thickness) was larger than group 1 (p < 0.001) and group 2 (p < 0.01) than in group 3. CHR was similar in groups 1 and 2. Systolic blood pressure was significantly increased in group 2 and showed a tendency to increase in group 1 as compared with group 3. The results confirmed the presence of concentric LVH related to a pressure overload in patients with TA, even when TA was complicated by severe AR.
Y Hashimoto; T Oniki; E Kaneko; A Hata; A Matsumura; T Kobayashi; F Numano
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Angiology     Volume:  44     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:  1993 Nov 
Date Detail:
Created Date:  1993-12-02     Completed Date:  1993-12-02     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  883-8     Citation Subset:  IM    
Third Department of Internal Medicine, Tokyo Medical and Dental University, School of Medicine, Japan.
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MeSH Terms
Aortic Valve Insufficiency / etiology*,  physiopathology
Blood Pressure
Heart Ventricles / ultrasonography
Hypertension / complications
Hypertrophy, Left Ventricular / etiology*,  physiopathology,  ultrasonography
Middle Aged
Takayasu Arteritis / complications*,  physiopathology,  ultrasonography

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