| Concealed arrhythmogenic syndromes: the hidden substrate of idiopathic ventricular fibrillation? | |
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MedLine Citation:
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PMID: 11334825 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In approximately 6--10% of survivors of cardiac arrest no cardiac abnormality can be identified despite extensive clinical evaluation. Autopsy data confirm that in a similar percentage of victims of sudden death no structural heart disease can be identified at post mortem evaluation. Occurrence of cardiac arrest in the absence of a substrate is defined 'idiopathic ventricular fibrillation' thus admitting that the cause for the arrhythmic event has remained unknown. We present data supporting the hypothesis that incompletely penetrant genetic defects may underlie at least some of these unexplained deaths. |
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Authors:
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S G Priori; C Napolitano; M Grillo |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Cardiovascular research Volume: 50 ISSN: 0008-6363 ISO Abbreviation: Cardiovasc. Res. Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-05-03 Completed Date: 2001-06-07 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0077427 Medline TA: Cardiovasc Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 218-23 Citation Subset: IM |
Affiliation:
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Molecular Cardiology, Fondazione Salvatore Maugeri, Via Ferrata 8, 27100 Pavia, Italy. spriori@fsm.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Death, Sudden, Cardiac
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etiology*,
pathology Electrocardiography Humans Long QT Syndrome / complications Pedigree Ventricular Fibrillation / genetics* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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