Document Detail


Concanavalin A-induced agglutination of Ehrlich ascites carcinoma cells during growth of the tumor in mice.
MedLine Citation:
PMID:  3808123     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
ConA-induced agglutination of Ehrlich ascites carcinoma (EAC) cells during development of the tumor in mice has been studied in vitro. EAC cells were incubated with different concentrations of ConA at 37 degrees C for various intervals of time and the cell aggregates of different sizes were scored under microscope. The older EAC cells (20-day-old) showed a decrease in cytoagglutination with respect to large aggregates formation compared to the younger (10-day-old) ones. The small aggregates formed by the 5-day-old EAC cells are dissociated by competition with alpha-methyl-D-mannoside but the large aggregates are not affected by the sugar treatment. The observed differences in the agglutination patterns are discussed in view of the influence of the lipid content of EAC cells and the ascites fluid on ConA-induced cytoagglutination.
Authors:
R Chatterjee; S Guha; J Chattopadhyay
Related Documents :
3089963 - Perturbations in cancer cell deformability and resistance to shear forces.
1531803 - A rapid and simple method for the purification of tumor cells from ascitic fluid of ova...
320953 - Alterations of alkaline phosphatase activity during adaptation of escherichia coli to p...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neoplasma     Volume:  33     ISSN:  0028-2685     ISO Abbreviation:  Neoplasma     Publication Date:  1986  
Date Detail:
Created Date:  1987-03-11     Completed Date:  1987-03-11     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0377266     Medline TA:  Neoplasma     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  685-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Carcinoma, Ehrlich Tumor / pathology*
Cell Aggregation / drug effects
Concanavalin A / pharmacology*
Lipid Metabolism
Methylmannosides / pharmacology
Mice
Chemical
Reg. No./Substance:
0/Methylmannosides; 11028-71-0/Concanavalin A; 51023-63-3/methylmannoside

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The "in vivo" effect of protein A on tumor growth.
Next Document:  Influence of ascorbic acid on the mutagenicity of N-methyl-N-nitrosoguanidine and nitrofurans studie...