Document Detail

Computerized tomographic nodule heterogeneity: present and future impact on indications for sublobar resections.
MedLine Citation:
PMID:  15310413     Owner:  NLM     Status:  MEDLINE    
With the advent of lung cancer screening, many nodules are being detected that are subsequently proven to be lung cancer. These nodules have different radiographic appearances and different biologic characteristics regarding their invasiveness and propensity for metastasis. These solid and part-solid nodules are now having surgeons reassess issues of lung sparing for early-stage lung cancer by not only considering smaller nodules as potentially appropriate for wedge resection or segmentectomies, but are also requiring surgeons to stratify these lesions by radiographic appearance. Data that argue for considering lesser resection of selected early-stage lung cancers, as well as the need for more prospectively accumulated facts that arise from trial designs like the original randomized Lung Cancer Study Group Trial, are discussed.
Harvey I Pass; Nasser K Altorki
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical lung cancer     Volume:  6     ISSN:  1525-7304     ISO Abbreviation:  Clin Lung Cancer     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-08-16     Completed Date:  2005-01-25     Revised Date:  2008-12-12    
Medline Journal Info:
Nlm Unique ID:  100893225     Medline TA:  Clin Lung Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  20-7     Citation Subset:  IM    
Department of Surgery and Oncology, Wayne State University and Karmanos Cancer Institute, Detroit, MI 48201, USA.
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MeSH Terms
Carcinoma, Non-Small-Cell Lung / pathology,  radiography*,  surgery*
Clinical Trials as Topic
Lung Neoplasms / pathology,  radiography*,  surgery*
Neoplasm Staging
Pneumonectomy / methods
Survival Analysis
Tomography, X-Ray Computed*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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