| Computerized measures of CT scans of alcoholics: thalamic region related to memory. | |
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MedLine Citation:
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PMID: 6336143 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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CT scans of 24 chronic alcoholics were analyzed by computer. Measures of thalamic CT density numbers and third ventricle/intracranial width ratio, as well as supraventricular measures of frontal and parietal CT density numbers, sulcal fluid area, and sulcal fluid volume, were obtained. Tests of long- and short-term memory and visuoperceptive functions were also administered. Results showed that alcoholics' long-term (but not short-term) memory performance correlates significantly with thalamic CT density numbers in the region of the dorsomedial nucleus and with third ventricle/intracranial width ratio, but not with supraventricular CT measures. These findings support the conclusions that (1) the midline thalamic region is involved in the mediation of long-term memory; (2) long- and short-term memory are separable on an anatomical as well as psychological basis; (3) there is a continuum of cognitive impairment encompassing alcoholic Korsakoff patients at one end of the spectrum and alcohol abusers at the other end and (4) computerized CT scan measures, including CT density numbers, contribute significantly to alcoholic CT research methodology. |
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Authors:
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C A Gebhardt; M A Naeser; N Butters |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Alcohol (Fayetteville, N.Y.) Volume: 1 ISSN: 0741-8329 ISO Abbreviation: Alcohol Publication Date: 1984 Mar-Apr |
Date Detail:
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Created Date: 1985-10-03 Completed Date: 1985-10-03 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8502311 Medline TA: Alcohol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 133-40 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alcoholism
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complications,
diagnosis,
radiography* Cerebral Ventriculography Humans Male Memory Disorders / diagnosis*, etiology Middle Aged Neuropsychological Tests Thalamic Nuclei / radiography* Tomography, X-Ray Computed |
| Grant Support | |
ID/Acronym/Agency:
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AA 05148/AA/NIAAA NIH HHS; AA-00187/AA/NIAAA NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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