| Computerized 2-lead resting ECG analysis for the detection of relevant coronary artery stenosis in comparison with angiographic findings. | |
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MedLine Citation:
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PMID: 18983288 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To assess the sensitivity and specificity of a new computer-enhanced resting electrocardiographic analysis device for the detection of coronary stenosis, 189 patients (aged 61.3+/-12.9 years, 57 women) scheduled for coronary angiography from 4 Asian centers were included in an observational study. Angiographic results were independently classified for hemodynamically relevant stenosis by 2 angiographers. The device calculated a severity score from 0 to 20. The score was significantly higher for patients with coronary stenosis (5.4+/-1.8 vs 1.7+/-2.1). The study device (cutoff 4.0) identified 73 of 77 patients with stenosis (sensitivity 94.8%, specificity 86.6%). Adjusted positive and negative predictive values were 78.4% and 97.1%, respectively (receiver operating characteristic area under the curve, 0.914 [95% confidence interval, 0.868-0.961]). Subgroup analysis showed no significant influence of sex, age, previous revascularization procedures, or participating center. The new computer-enhanced, resting electrocardiographic analysis device appears to identify patients with relevant coronary stenosis with high sensitivity and specificity. |
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Authors:
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Joji Hosokawa; Joseph T Shen; Michael Imhoff |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Congestive heart failure (Greenwich, Conn.) Volume: 14 ISSN: 1527-5299 ISO Abbreviation: Congest Heart Fail Publication Date: 2008 Sep-Oct |
Date Detail:
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Created Date: 2008-11-05 Completed Date: 2009-01-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9714174 Medline TA: Congest Heart Fail Country: United States |
Other Details:
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Languages: eng Pagination: 251-60 Citation Subset: IM |
Affiliation:
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From the Tokyo Heart Center, Kita-shinagawa, Shinagawa, Tokyo, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Coronary Angiography Coronary Artery Disease / diagnosis, physiopathology Coronary Stenosis / diagnosis*, physiopathology Electrocardiography / instrumentation, methods* Female Health Status Indicators Humans Male Middle Aged Models, Theoretical ROC Curve Sensitivity and Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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