Document Detail

Computer modeling to tailor therapy for congenital heart disease.
MedLine Citation:
PMID:  23881579     Owner:  NLM     Status:  MEDLINE    
The inherent structural and physiological complexity of congenital heart disease lends itself strongly to simulation. Complex hemodynamic and structural problems unique to congenital heart disease may be difficult to understand and the response to therapy or intervention uncertain. Methodologies borrowed from engineering, computing and mathematical sciences can be applied to such problems and used to inform clinical decisions. Therapy thus informed by modeling experiments has the potential to contribute significantly to improved clinical outcomes. This field remains in its infancy, and will only become used routinely if validation of current methods is carried out in the clinical setting.
Michael A Quail; Andrew M Taylor
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current cardiology reports     Volume:  15     ISSN:  1534-3170     ISO Abbreviation:  Curr Cardiol Rep     Publication Date:  2013 Sep 
Date Detail:
Created Date:  2013-07-24     Completed Date:  2014-03-11     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  100888969     Medline TA:  Curr Cardiol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  395     Citation Subset:  IM    
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MeSH Terms
Computer Simulation*
Heart Defects, Congenital / physiopathology,  surgery*
Heart Valve Prosthesis
Heart Ventricles / abnormalities
Hemodynamics / physiology
Hypoplastic Left Heart Syndrome / surgery
Materials Testing / methods
Models, Cardiovascular*
Prosthesis Design
Grant Support
FS/11/76/29037//British Heart Foundation; SRF/01/018//Department of Health; //British Heart Foundation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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