Document Detail


Computer methodology for simulation and prediction of alloimmune responses: expected antibody specificities.
MedLine Citation:
PMID:  6661908     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The methodology presented here was developed for simulating planned alloimmunization results, with regard to the type and number of expected antibody specificities. The computer program designed for this purpose was adapted to an immunogenetic model using Boolean algebra. It was written to help immunogeneticists avoid handling routine data preceding selection of donor-recipient pairs, specially concerning blood type alloimmunizations in animals: all of the donor-recipient combinations and the expected antibody specificities (their limit number being specified in each particular immunization program) are provided in the print-out.
Authors:
J Altarriba; I Zarazaga; B Amorena
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Computers in biology and medicine     Volume:  13     ISSN:  0010-4825     ISO Abbreviation:  Comput. Biol. Med.     Publication Date:  1983  
Date Detail:
Created Date:  1984-03-14     Completed Date:  1984-03-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1250250     Medline TA:  Comput Biol Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  265-70     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Domestic
Antibody Specificity*
Blood Group Antigens / immunology
Blood Grouping and Crossmatching
Cattle
Computers*
Immunization
Immunogenetics
Isoantibodies / biosynthesis*
Models, Biological
Chemical
Reg. No./Substance:
0/Blood Group Antigens; 0/Isoantibodies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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