| Computer-assisted detection of pulmonary embolism: evaluation of pulmonary CT angiograms performed in an on-call setting. | |
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MedLine Citation:
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PMID: 19862534 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The purpose of the study was to assess the stand-alone performance of computer-assisted detection (CAD) for evaluation of pulmonary CT angiograms (CTPA) performed in an on-call setting. METHODS: In this institutional review board-approved study, we retrospectively included 292 consecutive CTPA performed during night shifts and weekends over a period of 16 months. Original reports were compared with a dedicated CAD system for pulmonary emboli (PE). A reference standard for the presence of PE was established using independent evaluation by two readers and consultation of a third experienced radiologist in discordant cases. RESULTS: Original reports had described 225 negative studies and 67 positive studies for PE. CAD found PE in seven patients originally reported as negative but identified by independent evaluation: emboli were located in segmental (n = 2) and subsegmental arteries (n = 5). The negative predictive value (NPV) of the CAD algorithm was 92% (44/48). On average there were 4.7 false positives (FP) per examination (median 2, range 0-42). In 72% of studies <or=5 FP were found, 13% of studies had >or=10 FP. CONCLUSION: CAD identified small emboli originally missed under clinical conditions and found 93% of the isolated subsegmental emboli. On average there were 4.7 FP per examination. |
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Authors:
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Rianne Wittenberg; Joost F Peters; Jeroen J Sonnemans; Mathias Prokop; Cornelia M Schaefer-Prokop |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-10-28 |
Journal Detail:
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Title: European radiology Volume: 20 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-10 Completed Date: 2010-06-18 Revised Date: 2010-09-27 |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 801-6 Citation Subset: IM |
Affiliation:
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Department of Radiology, Academic Medical Centre, Amsterdam, The Netherlands. r.wittenberg@amc.uva.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult After-Hours Care / statistics & numerical data* Aged Aged, 80 and over Algorithms Angiography / statistics & numerical data* Artificial Intelligence Female Humans Male Middle Aged Netherlands / epidemiology Pattern Recognition, Automated / methods* Pulmonary Embolism / epidemiology*, radiography* Radiographic Image Enhancement / methods Radiographic Image Interpretation, Computer-Assisted / methods* Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed / statistics & numerical data* Young Adult |
| Comments/Corrections | |
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