Document Detail

Computer analysis of the early diastolic notch in Doppler sonograms of the uterine arteries.
MedLine Citation:
PMID:  8553494     Owner:  NLM     Status:  MEDLINE    
This article describes a set of processing and analysis techniques for automated identification and quantification of the early diastolic notch (EDN), a feature of Doppler sonograms from the uterine arteries which has been associated with adverse pregnancy outcomes such as preeclampsia and intrauterine growth retardation. Examples covering different sonogram types are provided to illustrate the effectiveness and reproducibility of the processing/analysis tools. Also, a receiver-operating characteristic-based evaluation of the EDN quantification and pulsatility indexes is presented, which examines the ability to predict hypertension and/or intrauterine growth retardation, using a set of uterine Doppler sonograms from 92 patients acquired at 18 weeks of gestation. In summary, the ROC results confirm the link between the EDN and abnormal pregnancy outcomes, and suggest that EDN quantification has a higher diagnostic accuracy than the pulsatility index, which characterises the flow waveform in a global manner and therefore does not take explicitly into account the localised nature of the EDN. Quantification of the EDN at 18 weeks of gestation appears to best predict the most severely abnormal pregnancy outcomes.
T Loupas; D A Ellwood; R W Gill; S Bruce; R A Fay
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ultrasound in medicine & biology     Volume:  21     ISSN:  0301-5629     ISO Abbreviation:  Ultrasound Med Biol     Publication Date:  1995  
Date Detail:
Created Date:  1996-02-20     Completed Date:  1996-02-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0410553     Medline TA:  Ultrasound Med Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1001-11     Citation Subset:  IM    
Ultrasonics Laboratory, CSIRO Division of Radiophysics, Sydney, Australia.
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MeSH Terms
Fetal Growth Retardation / physiopathology,  ultrasonography
Gestational Age
Hypertension / physiopathology,  ultrasonography
Image Processing, Computer-Assisted*
Pre-Eclampsia / physiopathology,  ultrasonography
Pregnancy Complications, Cardiovascular / physiopathology,  ultrasonography
Pregnancy Outcome*
Pulsatile Flow
ROC Curve
Reproducibility of Results
Signal Processing, Computer-Assisted
Ultrasonography, Doppler*
Ultrasonography, Prenatal*
Uterus / blood supply*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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