| Computer-aided Detection of Small Pulmonary Nodules in Chest Radiographs An Observer Study. | |
| | |
MedLine Citation:
|
PMID: 21963532 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
RATIONALE AND OBJECTIVES: To evaluate the impact of computer-aided detection (CAD, IQQA-Chest; EDDA Technology, Princeton Junction, NJ) used as second reader on the detection of small pulmonary nodules in chest radiography (CXR). MATERIALS AND METHODS: A total of 113 patients (mean age 62 years) with CT and CXR within 6 weeks were selected. Fifty-nine patients showed 101 pulmonary nodules (diameter 5-15mm); the remaining 54 patients served as negative controls. Six readers of varying experience individually evaluated the CXR without and with CAD as second reader in two separate reading sessions. The sensitivity per lesion, figure of merit (FOM), and mean false positive per image (mFP) were calculated. Institutional review board approval was waived. RESULTS: With CAD, the sensitivity increased for inexperienced readers (39% vs. 45%, P < .05) and remained unchanged for experienced readers (50% vs. 51%). The mFP nonsignificantly increased for both inexperienced and experienced readers (0.27 vs. 0.34 and 0.16 vs. 0.21). The mean FOM did not significantly differ for readings without and with CAD irrespective of reader experience (0.71 vs. 0.71 and 0.84 vs. 0.87). All readers together dismissed 33% of true-positive CAD candidates. False-positive candidates by CAD provoked 40% of all false-positive marks made by the readers. CONCLUSION: CAD improves the sensitivity of inexperienced readers for the detection of small nodules at the expense of loss of specificity. Overall performance by means of FOM was therefore not affected. To use CAD more beneficial, readers need to improve their ability to differentiate true from false-positive CAD candidates. |
| | |
Authors:
|
Diederick W De Boo; Martin Uffmann; Michael Weber; Shandra Bipat; Eelco F Boorsma; Maeke J Scheerder; Nicole J Freling; Cornelia M Schaefer-Prokop |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-9-30 |
Journal Detail:
|
Title: Academic radiology Volume: - ISSN: 1878-4046 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-10-3 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9440159 Medline TA: Acad Radiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 AUR. Published by Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Radiology, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Towards a dialogue between psychoanalysis and neuroscience: Connections that are both possible and n...
Next Document: Association of insulin resistance to different anthropometric measures and cardiovascular risk facto...