| Computer-based automated left atrium segmentation and volumetry from ECG-gated coronary CT angiography data: comparison with manual slice segmentation and ultrasound planimetric methods. | |
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MedLine Citation:
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PMID: 20938885 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Enlargement of the left atrium is a risk factor for cardiovascular or cerebrovascular events. We evaluated the performance of prototype software for fully automated segmentation and volumetry of the left atrium. MATERIALS AND METHODS: In 34 retrospectively ECG-gated coronary CT angiography scans, the end-systolic (LAVsys) and end-diastolic (LAVdia) volume of the left atrium was calculated fully automatically by prototype software. Manual slice segmentation by two independent experienced radiologists served as the reference standard. Furthermore, two independent observers calculated the LAV utilizing two ultrasound planimetric methods ("area length" and "prolate ellipse") on CTA images. Measurement periods were compared for all methods. RESULTS: The left atrial volumes calculated with the prototype software were in excellent agreement with the results from manual slice segmentation (r = 0.97 - 0.99; p < 0.001; Bland-Altman) with excellent interobserver agreement between both radiologists (r = 0.99; p < 0.001). Ultrasound planimetric methods clearly showed a higher variation (r = 0.72 - 0.86) with moderate interobserver agreement (r = 0.51 - 0.79). The measurement period was significantly lower with the software (267 ± 28 sec; p < 0.001) than with ultrasound methods (431 ± 68 sec) or manual slice segmentation (567 ± 91 sec). CONCLUSION: The prototype software showed excellent agreement with manual slice segmentation with the least time consumption. This will facilitate the routine assessment of the LA volume from coronary CTA data and therefore risk stratification. |
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Authors:
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R W Bauer; B Kraus; D Bernhardt; J M Kerl; T Lehnert; H Ackermann; F Vega-Higuera; T J Vogl |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2010-10-11 |
Journal Detail:
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Title: RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin Volume: 182 ISSN: 1438-9010 ISO Abbreviation: Rofo Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-24 Completed Date: 2010-12-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7507497 Medline TA: Rofo Country: Germany |
Other Details:
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Languages: eng Pagination: 1110-7 Citation Subset: IM |
Copyright Information:
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© Georg Thieme Verlag KG Stuttgart · New York. |
Affiliation:
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Institut für Diagnostische und Interventionelle Radiologie, Klinikum der Goethe-Universität, 60590 Frankfurt, Germany. ralfwbauer@aol.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angiography / methods* Cardiac-Gated Imaging Techniques* Contrast Media / administration & dosage Coronary Angiography / methods* Diastole / physiology Echocardiography / methods* Female Heart Atria / radiography* Humans Image Processing, Computer-Assisted / methods* Imaging, Three-Dimensional / methods* Iopamidol / analogs & derivatives, diagnostic use Male Middle Aged Organ Size / physiology Retrospective Studies Sensitivity and Specificity Software Statistics as Topic Systole / physiology Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 62883-00-5/Iopamidol; 78649-41-9/iomeprol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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