| Computed tomography-guided percutaneous acetic acid injection therapy for functioning adrenocortical adenoma. | |
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MedLine Citation:
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PMID: 14671174 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We reported the outcomes of computed tomography (CT)-guided percutaneous acetic acid injection therapy for functioning adrenocortical adenomas. With the patient in a prone position, the puncture needle was inserted vertically downward into the adenoma with frequent CT scanning. After confirmation by pilot injection with contrast medium, a small aliquot of 40-50% acetic acid was injected and repeated. Between 1997 and 2002, 18 sessions of CT-guided injection therapy, including one session of ethanol injection, were performed on 10 patients (five patients with primary aldosteronism and five patients with Cushing's or subclinical Cushing's syndrome) without any complications except transient upper abdominal pain during the acetic acid injection. The follow-up period ranged from 5-69 months. The treatment resulted in almost an extirpation of the adrenocortical hyperfunction in seven patients after one or two sessions. CT-guided percutaneous acetic acid injection might be a simple, cost-effective, and far less invasive treatment for small functioning adrenocortical adenomas. |
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Authors:
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Shigeru Minowada; Tetsuya Fujimura; Naoki Takahashi; Hiroichi Kishi; Kanehiro Hasuo; Manabu Minami |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of clinical endocrinology and metabolism Volume: 88 ISSN: 0021-972X ISO Abbreviation: J. Clin. Endocrinol. Metab. Publication Date: 2003 Dec |
Date Detail:
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Created Date: 2003-12-12 Completed Date: 2004-01-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0375362 Medline TA: J Clin Endocrinol Metab Country: United States |
Other Details:
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Languages: eng Pagination: 5814-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Urology, International Medical Center of Japan, Tokyo 162-8655, Japan. sminowad@imcj.hosp.go.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acetic Acid
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administration & dosage*,
adverse effects Adrenal Cortex Neoplasms / complications, drug therapy*, physiopathology, radiography Adrenocortical Adenoma / complications, drug therapy*, physiopathology, radiography Adult Aged Cushing Syndrome / etiology Drug Administration Schedule Female Humans Hyperaldosteronism / etiology Hypertension / etiology Injections, Intralesional Male Middle Aged Pain / etiology Tomography, X-Ray Computed* / methods Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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64-19-7/Acetic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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