| Computed tomography for the detection of free-floating thrombi in the right heart in acute pulmonary embolism. | |
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MedLine Citation:
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PMID: 20809126 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVES: The aim of this study was to assess the prevalence of free-floating thrombi in the right heart (FFT) and the accuracy of computed tomography (CT) for their detection in pulmonary embolism (PE). METHODS: We studied 340 consecutive patients presenting with PE. All patients underwent CT and echocardiography. RESULTS: The prevalence of FFT was 3.5% in the global population of PE and 22% in high-risk PE. Dyspnoea, cardiogenic shock, cardiac arrest and tachycardia were more frequently found in patients with FFT (p = 0.04, p < 0.0001, p = 0.0003 and p = 0.01, respectively). Sensitivity and specificity of CT for the detection of FFT were 100% (95% confidence interval: 74%-100%) and 97% (95%-99%), whereas positive and negative predictive values were 57% (34%-78%) and 100% (99%-100%). Among patients with FFT, right ventricular dilation was always detected by CT, whereas no right ventricular dilation was found among patients with a false diagnosis of FFT performed by CT (p < 0.0001). CONCLUSION: Prevalence of FFT is 3.5% and differs according to the clinical presentation. Detection of FFT by CT is feasible and should lead to echocardiography being promptly performed for the confirmation of FFT. |
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Authors:
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Nicolas Mansencal; David Attias; Vincent Caille; Julien Desperramons; Julie Guiader; Mostafa El Hajjam; Pascal Lacombe; Imad Abi Nasr; François Jardin; Antoine Vieillard-Baron; Olivier Dubourg |
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Publication Detail:
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Type: Journal Article Date: 2010-08-31 |
Journal Detail:
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Title: European radiology Volume: 21 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-02-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 240-5 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Université de Versailles-Saint Quentin (UVSQ), Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de Référence des Maladies Cardiaques Héréditaires, Boulogne, France, nicolas.mansencal@apr.aphp.fr. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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