Document Detail


Computed tomography of a cat with primary intratracheal lymphosarcoma before and after systemic chemotherapy.
MedLine Citation:
PMID:  22058360     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 12 yr old male neutered domestic shorthair cat presented with worsening tachypnea of 1 mo duration and open mouth breathing. Radiographs revealed tracheal narrowing at the thoracic inlet. Computed tomography (CT) revealed a contrast enhancing 8-cm long fusiform mass within the dorsal tracheal membrane. Tracheobronchoscopy confirmed the presence of the tracheal mass at the thoracic inlet, and lymphoma was diagnosed based on uniformly atypical lymphoid cells on aspirated bronchoalveolar lavage fluid. The cat was treated with combination chemotherapy consisting of cyclophosphamide, vincristine, doxorubicin, and prednisolone. Thoracic radiographs and CT performed 1 mo after completion of the 6 mo chemotherapy protocol revealed resolution of the tracheal mass. The cat remained clinically normal at 21 mo after treatment.
Authors:
Brandy Dugas; John Hoover; Robert Pechman
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Animal Hospital Association     Volume:  47     ISSN:  1547-3317     ISO Abbreviation:  J Am Anim Hosp Assoc     Publication Date:    2011 Nov-Dec
Date Detail:
Created Date:  2011-11-07     Completed Date:  2012-03-01     Revised Date:  2012-04-04    
Medline Journal Info:
Nlm Unique ID:  0415027     Medline TA:  J Am Anim Hosp Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e131-7     Citation Subset:  IM    
Affiliation:
Internal Medicine Department, Oklahoma State Veterinary Teaching Hospital, Stillwater, OK, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
Cat Diseases / drug therapy*,  radiography
Cats
Cyclophosphamide / administration & dosage
Doxorubicin / administration & dosage
Lymphoma, Non-Hodgkin / drug therapy,  veterinary*
Male
Prednisolone / administration & dosage
Tomography, X-Ray Computed / veterinary
Tracheal Neoplasms / drug therapy,  veterinary*
Vincristine / administration & dosage
Chemical
Reg. No./Substance:
23214-92-8/Doxorubicin; 50-18-0/Cyclophosphamide; 50-24-8/Prednisolone; 57-22-7/Vincristine

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