| Computed tomographic perfusion in the management of aneurysmal subarachnoid hemorrhage: new application of an existent technique. | |
| | |
MedLine Citation:
|
PMID: 15670379 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Cerebral blood flow (CBF) alterations are common after aneurysmal subarachnoid hemorrhage (SAH). Treatment of delayed cerebral ischemia in this setting depends on timely and accurate diagnosis. Techniques to measure cerebral blood flow are useful and important. Computed tomographic (CT) perfusion imaging is a technique for the measurement of CBF, cerebral blood volume, and time to peak. It is a fast and inexpensive brain imaging modality that offers promise in the management of patients with SAH. METHODS: CT perfusion imaging was performed in 10 patients with aneurysmal SAH when neurological changes raised suspicions of cerebral ischemia. Quantitative values for CBF, cerebral blood volume, and time to peak were obtained in each study. The case history, CT perfusion results, and an analysis of how patient management was influenced are presented for each patient. RESULTS: A total of 17 CT perfusion studies were performed. Five studies showed evidence of cerebral ischemia, leading to endovascular treatment of vasospasm. Eight studies excluded cerebral ischemia, and two studies identified cerebral hyperemia, resulting in adjustments in hyperdynamic therapy. CT perfusion was used to help predict a poor prognosis and withhold aggressive intervention in two patients with poor Hunt and Hess grades. Time-to-peak values identified regions of cerebral ischemia more readily than CBF or cerebral blood volume values. CONCLUSION: CT perfusion imaging can be used to identify patients with delayed cerebral ischemia after SAH and to guide medical and endovascular therapy. The findings can lead to alterations in patient management. |
| | |
Authors:
|
Mark R Harrigan; Christopher R Magnano; Lee R Guterman; L Nelson Hopkins |
Related Documents
:
|
1532689 - Comparison of three computer scanning modes as an interface method for persons with cer... 16567439 - Transcranial contrast imaging of cerebral perfusion in patients with space-occupying in... 8957809 - Ct and mri in a girl with late-onset ornithine transcarbamylase deficiency: case report. 15295399 - Postpartum cerebral angiopathy: an important diagnostic consideration in the postpartum... 16132929 - Cerebral scedosporiosis: an emerging fungal infection in severe neutropenic patients: c... 15967439 - Intravenous infusion of immortalized human mesenchymal stem cells protects against inju... 1877429 - Idiopathic hemochromatosis. 19018049 - Mri of pelvic floor dysfunction: review. 11518269 - A new rabbit model for the study on cervical compressive myelopathy. |
Publication Detail:
|
Type: Case Reports; Journal Article; Review |
Journal Detail:
|
Title: Neurosurgery Volume: 56 ISSN: 1524-4040 ISO Abbreviation: Neurosurgery Publication Date: 2005 Feb |
Date Detail:
|
Created Date: 2005-01-26 Completed Date: 2006-05-30 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7802914 Medline TA: Neurosurgery Country: United States |
Other Details:
|
Languages: eng Pagination: 304-17; discussion 304-17 Citation Subset: IM |
Affiliation:
|
Department of Surgery, Division of Neurosurgery, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA. mharrigan@uabmc.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Brain Ischemia / etiology Cerebrovascular Circulation Female Humans Male Middle Aged Subarachnoid Hemorrhage / complications, physiopathology* Tomography, X-Ray Computed* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Surgical management of 10 genitofemoral neuralgias at the Louisiana State University Health Sciences...
Next Document: Multistage epilepsy surgery: safety, efficacy, and utility of a novel approach in pediatric extratem...