Document Detail

Computed tomographic changes associated with the prepatent and early patent phase of dirofilariasis in an experimentally infected dog.
MedLine Citation:
PMID:  20402396     Owner:  NLM     Status:  MEDLINE    
Evolution of pulmonary arterial and parenchymal changes as assessed with computed tomography (CT) is described in a dog experimentally infected with Dirofilaria immitis. The dog was imaged 125, 168, 216, and 402 days after infection. Initial changes during the prepatent phase of infection included enlargement of the peripheral caudal lobar pulmonary arteries and intermittent periarterial interstitial infiltrates. The changes were progressive, involving additional arteries over time, but remained mild. With the presence of adult filariae a filling defect was observed in the caudal lobar pulmonary artery using CT angiography. Recognizing thoracic CT findings associated with the prepatent phase of canine heartworm infection may be important in endemic areas.
Gabriela S Seiler; Thomas J Nolan; Eleanor Withnall; Caryn Reynolds; James B Lok; Meg M Sleeper
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association     Volume:  51     ISSN:  1058-8183     ISO Abbreviation:  Vet Radiol Ultrasound     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-04-20     Completed Date:  2010-07-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9209635     Medline TA:  Vet Radiol Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  136-40     Citation Subset:  IM    
Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, 3900 Spruce Street, Philadelphia, PA 19104-6010, USA.
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MeSH Terms
Angiography / veterinary
Contrast Media
Dirofilaria immitis / isolation & purification
Dirofilariasis / blood,  pathology*,  radiography*
Disease Models, Animal
Disease Progression
Dog Diseases / blood,  parasitology*,  pathology,  radiography*
Pulmonary Artery / parasitology,  radiography
Specific Pathogen-Free Organisms
Tomography, X-Ray Computed / methods,  veterinary*
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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