Document Detail

Computed tomographic angiography and venography for young or nonhypertensive patients with acute spontaneous intracerebral hemorrhage.
MedLine Citation:
PMID:  21088241     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: we compared the effectiveness of using computed tomographic angiography and venography (CTAV) with digital subtraction angiography (DSA) in young or nonhypertensive patients with acute spontaneous intracerebral hemorrhage.
METHODS: we prospectively recruited 109 young (age between 18 and 45 years) or nonhypertensive patients with acute spontaneous intracerebral hemorrhage for this comparative study. All patients had CTAV using multidetector CT with 64 detectors. They were then scheduled to have catheter angiography the next day. Radiological data were collected for blinded analysis.
RESULTS: DSA-positive pathologies causing hemorrhage were identified in 37 (33%) patients, which included cerebral arteriovenous malformation in 22 cases. The positive and negative predictive values of CTAV for DSA-positive pathologies causing hemorrhage were 97.3% (95% CI, 88.3%-99.9%) and 100% (95% CI, 95.9%-100%), respectively.
CONCLUSIONS: CTAV was able to detect DSA-positive pathologies causing acute spontaneous intracerebral hemorrhage in young (age between 18 and 45 years) or nonhypertensive patients with high positive and negative predictive values.
George Kwok Chu Wong; Deyond Yung Woon Siu; Jill Morales Abrigo; Wai Sang Poon; Federick Chun Pong Tsang; Xian Lun Zhu; Simon Chun Ho Yu; Anil Tejbhan Ahuja
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-11-18
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  42     ISSN:  1524-4628     ISO Abbreviation:  Stroke     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-28     Completed Date:  2011-01-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  United States    
Other Details:
Languages:  eng     Pagination:  211-3     Citation Subset:  IM    
Division of Neurosurgery, Department of Imaging, Prince of Wales Hospital, The Chinese Univeristy of Hong Kong, Hong Kong, China.
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MeSH Terms
Cerebral Hemorrhage / etiology,  radiography*
Intracranial Arteriovenous Malformations / complications,  radiography*
Middle Aged
Sensitivity and Specificity
Tomography, X-Ray Computed*

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